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By a similar token, our headache diagnostic questionnaire captured episodic migraine and TTH, while all chronic cases were subsumed under headache on ≥15 days/month [35].
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This is an uncommon, but probably under-diagnosed and under-reported headache, because patients often feel embarrassed to give details about their intimate sexual activities.
Indeed, most patients in the study of Kropp et al. [17] suffered substantially under headaches.
In the study from Boot et al. [ 13] adverse events were reported as transient self-limiting bronchospasm starting within 12 minutes after drug inhalation (8 patients under NK-1/NK-2 andagonist and 4 patients under placebo), headache (5 patients under NK-1/NK-2 andagonist and 3 patients under placebo), and self-limiting dyspneia (2 patients under NK-1/NK-2 andagonist and 5 patients under placebo).
Area-under-the-headache curve.
This high percentage points to headache under-recognition and under-estimation in low and middle income countries [7].
Pediatric headache remains under-recognized, under-diagnosed and under-treated.
Another primary endpoint, difference in the area under the headache score curve (AUC) 0-4 h after treatment was not significant (p = 0.10).
Immediately before threshold evaluation, untreated hypertensive patients had higher than normal blood pressure levels, while hypertensive patients under treatment, headache patients without hypertension and control subjects had normal blood pressure values.
Headache Under-Response to Treatment.
Headache under-response to treatment questionnaire.
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