Sentence examples for under conserved from inspiring English sources

The first test compares the "nearly neutral" model (M1a) with codons evolving under conserved (0<ω0<1) and neutral (ω1 = 1) evolution, with a positive selection branchXsites model that includes a third, positive rate ratio class (ω2>1) for a fraction of sites evolving on the foreground branch.

Some conserved under-represented codon pairs contained the stop-codon in +1 or +2 frame.

Thus, the advantage of the relative conservation method is the capability to discriminate SLiMs conserved under constraints of the integral protein from those conserved to serve as functional motifs.

This algorithm identifies the most conserved nucleotide motifs within a set of homologous DNA sequences, under the premise that functional regulatory elements are more highly conserved under natural selection than non-functional DNA sequences [29].

Operons with essential genes should be more conserved under the recombination model if linkage was under stronger purifying selection for pairs of these genes, which is plausible and has been observed in yeast (Pal and Hurst 2003).

Our analysis shows that recessive disease genes are under-represented among highly conserved genes.

Non-synonymous single nucleotide polymorphisms (nsSNPs) are under-represented at evolutionarily conserved sites in HERG, but distribute randomly in KCNQ1.

We performed a Fisher's exact test with Bonferroni correction (z-value cutoff = 1) to identify functional classes over- or under-represented in highly conserved and hyper-variable groups (see Methods for details).

Therefore, it is possible that the greater degree of conservation exhibited by dominant disease genes vs. recessive disease genes is an effect of the higher likelihood of fixation of slightly deleterious non-synonymous mutations in the recessive disease genes coupled with an under-representation of highly conserved genes in this same dataset.

The voucher specimen for the same is conserved under the reference number INTERCEDD/034.

This method has an advantage that the total energy of the beam is conserved under paraxial approximation.