Sentence examples for under a polygenic model from inspiring English sources

Heritability, with age and sex included as covariates, was estimated using SOLAR under a polygenic model [37].

Heritability was estimated under a polygenic model with environmental effects estimated using spouses.

The expected percentage of genetic variance explained by each of the ~2600 1 Mb windows is about 0.04% under a polygenic model.

> -wrap-foot> Some degree of genomic over-dispersion (genomic inflation) is expected under a polygenic model even in the absence of population stratification and other technical artifacts (20), and the meta-analysis showed modest evidence of over-dispersion (λ = 1.10) for the core 318 094 SNPs typed on Illumina HumanHap 300 BeadChips platform (Fig.  1, Supplementary Material, Fig. S2).

Thus, for the no-versus-one QTL test, phenotypes were simulated under H0, assuming a polygenic model with the trait heritability detailed in Table  1.

The rejection threshold of H0 and the chromosome-wide level of significance of H1 were estimated by 10,000 simulations under the H0 hypothesis with a polygenic model using heritability coefficients estimated by Recoquillay et al. [ 9].

Genome Wide Association Analysis was conducted using a polygenic model.

We build a polygenic model for complex traits that distinguishes candidate trait-relevant variants from the rest of the genome.

In part I, residuals are derived from a polygenic model, removing additive polygenic effects and possibly important lower-order effects or confounding factors.

To determine a possible mode of inheritance we fitted nine models, including four Mendelian models, a polygenic model, a polygenic plus Mendelian model, an environmental model, no major type, and a full model with arbitrary transmission probabilities (general) as described in Materials and methods.

Heritability analysis was performed using a polygenic model.