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We compare these models using simulated data sets of allele-specific read counts under a null scenario in which there is bias (B≠0.5) and no allelic imbalance (R = 1) and simulated data sets with both bias and allelic imbalance (R≠1).
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A Null scenario was included in this model.
When simulating phenotype data, we considered a null scenario of no association vs. a simple alternative scenario of one X-linked causal variant.
The minimum-ecoregion scenario (A) was a reference "null" scenario aimed at the representation of all species in the minimum number of ecoregions in the world; threats to species and economic cost of each ecoregion were not considered.
The total health benefits of an intervention were computed by comparing the number of healthy life years lived in the population in a particular intervention scenario with the total number of healthy life years lived in the population under the null scenario.
We compared these results with a reference "null" scenario that minimizes the total number of ecoregions in the final solution, regardless of human threats and economic costs.
Across the four anti-HTs under evaluation including null scenario, the highest NMB for each iteration was selected.
S values are obtained from 1,000 trees simulated under a null model of allopatric divergence (scenario b in Figure 4).
The null scenario in the three cardiovascular risk groups has a 0 (zero) probability of being cost effective.
We compared the performance of the different CTDs against the null scenario in which the amount of stimulus held at a site is exponentially distributed.
The reference single null scenario is detailed.
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