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Our results demonstrate the potential for using peptide modulators of Src activity as a tool for uncovering the function of Src in cells.
In the last decade, the discovery of oncogenes diverted interest away from studies of cellular metabolism in tumors towards those aimed at uncovering the function of oncogenes that control metabolism.
Aiming at uncovering the function of zebrafish prp2 gene, two MOs (prp2-MO1 and prp2-MO2) for targeting the prp2 mRNA were designed and injected into one cell stage zebrafish embryos.
However, uncovering the function of specific microRNA families has been limited by the lack of technologies for in vivo analysis.
Uncovering the function of these expressed pseudogenes would be a major step to fully understanding plant-pathogen interactions.
Previous studies aimed at uncovering the function of PICH by siRNA had yielded inconsistent results (Baumann et al. 2007; Hubner et al. 2010; Kurasawa and Yu-Lee 2010; Leng et al. 2008).
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Lee is being recognized for uncovering the functions of long, noncoding RNA in epigenetic regulation.
"Part of the work that's going to be really interesting in the future is uncovering the functions of some of those genes," she says.
Despite the recent progress in uncovering the functions of neural glycans, much is still unknown about their roles in the development, maintenance, and disease of the nervous system.
Over the last decade, much progress has been made in uncovering the functions of individual PDE4 variants in the rodent heart [ 26].
To date, there are more and more growing evidences uncovering the functions of many viral proteins to regulate autophagy through different cellular pathways.
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