However, Keller et al. have uncovered a modification of the T1 segment that has been overlooked until now.
These results strongly argue that, if hENT1 were the primary target for any of these drugs as widely suspected in the clinic, more potent drugs should be uncovered through chemical modification of existing ones.
Researchers at the Massachusetts Institute of Technology, led by neurobiologist Li-Huei Tsai, have now uncovered a chemical modification of DNA that regulates gene activity and dictates whether a memory is too old for reconsolidation in mice.
We uncovered unique skeletomuscular modifications in workers that presumably increase power and flexibility of head thorax articulation, emphasizing that workers are not simply wingless versions of queens.
In our analysis of epigenetic control by histone modification, we uncovered an difference between broad and peak promoters.
We uncovered three types of modifications made to technology artifacts: personalization, customization, and inventions.
A survey of millions of these modifications has uncovered a handful associated with body mass index, a measure of height and weight.
Emerging evidence has uncovered that histone tail modifications also influence mitotic chromosome condensation.
As secondary analyses, we studied interaction between temperature and obesity (BMI > 30 at the first visit in this dataset) to uncover possible effect modification, because obesity itself is considered as a low-grade inflammation state [ 24].
Remarkably, they uncovered a potentially novel Rab1 modification, which was mediated by a different effector AnkX.
By studying how the chromatin template contributes to the dynamic gene expression induced downstream of the JAK-STAT signaling pathway, we have uncovered relationships between specific histone modifications and RNA processing.
