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The comparative RAD21 binding analysis in ESCs versus EBs also uncovered changes in the CTCF dependent RAD21 binding sites, revealing the dynamic CTCF dependent RAD21 binding mode mentioned above.
We wished to examine rates of mRNA decay in C2C12 muscle cells for three reasons: (i) Previous studies have uncovered changes in mRNA stability that are essential for differentiation in this cell type [11] [14].
In addition, proteomics analysis of losartan- vs. vehicle-treated RDEB skin uncovered changes in multiple proteins related to tissue inflammation.
However, no studies performed to date have uncovered changes in cortical thickness that enable this shift from local to global visual processing at approximately 6 years of age.
In addition, we uncovered changes in the presynaptic neuron; in particular, defects in anterograde axonal transport and changes in localization of activated ERK.
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The raid, and the trove of evidence it uncovered, changed the way law enforcement across North America investigated the FLDS, turning what had been a relatively unknown group of polygamists into a household name.
Here, we first uncover changes in intestinal architecture, cell number, and cell composition upon aging.
Furthermore, the result of the verification is compared bit-wise to the current database, thus being able to uncover changes done directly in the underlying file system.
The TDI score seems to uncover changes in the olfactory capacity in MS patients.
Pathway analysis has emerged as an alternative or compensation for conventional gene analysis, because it can cover both conserved and not conserved changes within small sample populations and can uncover changes that otherwise would have been overlooked by conventional methods.
In order to uncover changes in groups of functionally interconnected genes we utilised two online analysis tools the Database for Innovation, Visualization and Integrated Discovery (DAVID; [61] and Ingenuity Pathway Analysis (IPA).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com