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In this study, we employed S89G-DMP1 micentomice to uncover the function of DMP1-PG during astrocytes maturation and maintenance of BBB integrity.
This hypothesis will have to be investigated in the future and further genetic and molecular analyses on docs1 mutant roots will be needed to uncover the function of the DOCS1 gene in these processes.
Future research to uncover the function of this gene may reveal novel insights into the molecular alterations of melanocytic nevi implicated in melanoma progression.
Gene expression pattern data has been used in the past to uncover the function of a gene.
Thus, to uncover the function of CD11ahiFcγRIIIhi B cells, we assessed their cytokine production using intracellular staining and ELISA.
The results from the model analysis offered additional details on known regulatory mechanisms and also helped to uncover the function of less studied genes on metabolic regulation.
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Tissue or cell-specific knockout studies of Dicer have been performed to uncover the functions of miRNAs during the development of cells including embryonic stem cells [3], female germline cells [4], testis Sertoli cells [5], pancreatic islet cells [6], lung epithelial cells [7], and skeletal chondrocytes [8].
In order to further uncover the functions of the genes and gene networks that are involved in controlling the yeast ionome we performed exhaustive significance clustering.
To uncover the functions of T. thermophilus RNases in vivo, we successfully disrupted 12 of the 15 putative T. thermophilus HB8 RNase genes.
Further research is needed to uncover the functions of these genes and their roles in developmental processes such as follicle assembly.
While the pathogenic E. coli strains are of great interest medically, they are not typically the focus of intense biochemical study to uncover the functions of their novel metabolic genes.
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