Sentence examples for uncoupling function from inspiring English sources

One of these studies suggests that UCPs may be involved in PPAR dependent gene transactivation through intrachromosomal looping next to their uncoupling function in the mitochondria [31].

This uncoupling function of the MVC may have been key to the evolutionary success of songbirds or oscines (Passeriformes: Passeri).

This result strongly suggests that UCP1 induction, associated with improved OxPHOS machinery, was effective in its uncoupling function.

FAs are considered the UCP2 cycling/wobbling substrates/cofactors, respectively, essential for their uncoupling function (6, 7, 12, 18, 20, 53).

However, it should be emphasized that a direct uncoupling function of UCP2 is not accepted universally [6,7] and, furthermore, that studies into the effects of UCP2 activity on GSIS are equivocal.

These cells showed a significant level of uncoupling when mitochondrial function was tested in the presence of oligomycin (figure 3B).

Uncoupling protein-1 (UCP1) functions to uncouple oxidative phosphorylation and converts the proton gradient energy to heat to maintain body temperature.

Given the strong correlation between p53 and downstream apoptotic events, we further examined whether blocking p53 mitochondrial translocation by mitochondrial uncoupling affected mitochondrial functions and apoptosis.

We report here that CAPE increases glucose uptake in C2C12 muscle cells by 225 ± 21% at 50 μM, and that activation of AMPK is a consequence of the metabolic stress resulting from an uncoupling-type disruption of mitochondrial function (complete uncoupling at 50 μM).

It expresses a unique protein, uncoupling protein 1 (Ucp1), which functions to uncouple oxidative phosphorylation and converting this proton gradient energy into heat to maintain normal body temperature.

These growth factor and cytokine-mediated interactions typically lead to stimulation of both osteoclast and osteoblast function with uncoupling and imbalance in bone remodelling.