Sentence examples for uncoupling agent from inspiring English sources

Next, maximal uncoupler-stimulated respiration (State 3u) was detected by the administration of the uncoupling agent carbonylcyanide-4-trifluorometh-oxyphenylhydrazone (FCCP).

Oxygen-consuming glucose oxidase and a potent mitochondrial uncoupling agent FCCP (4-trifluoromethoxy carbonyl cyanide phenylhydrazone) was used as a reference.

Cultivations were carried out in presence of an uncoupling agent, hexanoic acid, as a model weak acid, on several initial concentrations and at different incubation temperatures.

Cultures exposed to DHT were treated over a time course with the mitochondrial toxins oligomycin (binds ATP synthase to inhibit oxidative phosphorylation), rotenone (inhibits the electron transport of complex I) and FCCP, a protonophore uncoupling agent (Fig. 3E,F).

A modified version of a mitochondrial uncoupling agent can ameliorate fatty liver disease in rats, without apparent toxicity.

Compared to 10 μmol/L carbonyl cyanide m-chlorophenylhydrazone (CCCP, a proton uncoupling agent, Fig. 3H, I and Supplementary Video S3), 0.1 μmol/L NE shows markedly lower thermogenic efficacy (Fig. 3J).

Based on their catechol structure, both inhibitors are potential uncoupling agents, but only tolcapone shows this effect in vitro at clinically relevant concentrations.

Therefore, we treated our fibroblast cell cultures with the mitochondrial uncoupling agents valinomycin and CCCP or the superoxide generator H2O2.

According to some authors, these compounds may directly interfere with (platelet) mitochondrial function, mainly acting as uncoupling agents [ 33].

The transport of charge through artificial lipid membranes has been studied for a great variety of uncoupling agents.

A small group of compounds called uncoupling agents cause unrestrained oxygen uptake in the absence of ADP.