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It would be interesting to explore the effectiveness in other age groups with uncontrolled, treated or untreated hypertension.
Participants with hypertension were categorized into one of the following four subgroups: (1) aware (with physician' diagnosis) and controlled treated to target levels of < 140/90 mmHg, (2) aware and treated, but not reaching target blood pressure values of < 140/90 mmHg, i.e. uncontrolled treated, (3) aware, but not treated, (4) unaware of hypertension.
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We were unable to distinguish between newly diagnosed hypertension vs. uncontrolled hypertension treated for the first time using claims data.
Thereof 1120 patients remained in the study because of uncontrolled (but treated) hypertension and/or a relevant comorbidity.
Hence 1120 patients with uncontrolled but treated hypertension and/or at least one relevant comorbid disorder continued in the study.
A descriptive analysis was done to illustrate the proportion of patients with uncontrolled (but treated) hypertension at each time point.
A separate 12-week trial [ 61] investigated nebivolol (5 40 mg/day) as add-on therapy to lisinopril (10 20 mg/day) or losartan (50 100 mg/day) in patients with untreated or uncontrolled hypertension treated with lisinopril or losartan.
Al Obeidan et al. published the largest prospective study of 33 consecutive eyes with uncontrolled UG treated with NPDS with MMC and implantation of either the T-Flux implant (Ioltech, La Rochelle, France) or SK gel (Corneal Laboratories, Paris, France).
This study documents the baseline and treatment outcome data collected during a 12-week budesonide/formoterol maintenance and reliever therapy in 862 Asian patients with partially controlled or uncontrolled asthma, treated in a real-life clinical practice setting.
Even though the mean BP values in both study arms were below recommended BP values for ABPM in T1, the proportion of patients with uncontrolled (but treated) hypertension (as defined: at least one of the six ABPM thresholds was exceeded) in the intervention group amounted to 76.9% (N = 356) and in the control group to 71.6% (N = 327) (cf. Table 4).
If uncontrolled or inappropriately treated, AR can severely impair quality of life for children and their families.
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