Uncontrolled inflammation may contribute to infection, autoimmunity, allergies, or cancer.
Any imbalance favoring NF-κB bioactivity will results in uncontrolled inflammation.
Idiopathic Subtenon triamcinolone, oral prednisone, oral methotrexate Uncontrolled inflammation with previous regimen 4266 M Bilateral chronic intermediate uveitis.
HLA B27 positive Oral prednisone Uncontrolled inflammation despite maximal dose of oral prednisone F female, M male.
Obviously, these molecular mechanisms of action of glucocorticoids are very well appropriate to counteract the uncontrolled inflammation that characterized sepsis.
One of the major obstacles in the treatment of severe electrical burns is properly handling the resulting uncontrolled inflammation.
However, under conditions of uncontrolled inflammation and in autoimmune diseases, dysregulated production and/or action of inflammatory cytokines can be detrimental and pathogenic.
Sepsis results from a dysregulated host response to infection leading to uncontrolled inflammation and organ dysfunction and potentially a hypotensive state known as septic shock [2].
Ascorbic acid attenuates endothelial dysfunction in animal models of acute lung injury (ALI) [21] a condition characterized by uncontrolled inflammation [22].
Such systems produce an external insult to the joint without the need of any chemical or surgical intervention, avoiding the risks of infection or of uncontrolled inflammation and allowing the creation of standardized injuries.
With respect to the cataract findings, it was not possible to clearly determine in all cases whether it was due to age, past/present steroid use, or uncontrolled inflammation.
