Sentence examples for uncontrolled accumulation of from inspiring English sources

Leukemia is a malignant disease characterized by the uncontrolled accumulation of abnormal white blood cells.

The uncontrolled accumulation of these molecules in wine leads to sensorial defects that compromise wine quality.

However, while the ATP driving force module is effective for increasing product formation, uncontrolled accumulation of intermediate metabolites likely led to metabolic imbalance and thus to cell growth inhibition.

There is considerable evidence supporting the view that peri-implant diseases are infectious in nature and mainly linked to an uncontrolled accumulation of bacterial plaque biofilms [1].

Thus, one signaling cycle or constant action of NF-κB from LMB or CHX, respectively, induced opposite functional consequences: premature termination or uncontrolled accumulation of target gene transcripts.

However, misregulation and persistence of myofibroblasts can lead to uncontrolled accumulation of matrix proteins, tissue stiffening, and ultimately disease.

It is a widely accepted view that uncontrolled proliferation and accumulation of contractile myofibroblasts underlies the pathogenesis of DC [ 3].

Among oncohematological diseases, acute lymphoid leukemia (ALL) and acute myeloid leukemia (AML) are characterized by the uncontrolled production and accumulation of blasts that can lead to death.

This results in uncontrolled cell proliferation and accumulation of specific (epi genetic changes in the host cell genome, driving progression to a malignant phenotype [ 2, 3].

Because the previous long-term experimental evolution with serial passages lacked explicit size selections, the selection target and its pressure were uncontrolled, allowing for the accumulation of mutations unrelated to size changes.

Furthermore, these signaling events may be accompanied by, uncontrolled macropinocytosis, resulting in the accumulation of macropinosomes in the cytosol that overwhelm the capacity of the cells to adapt to the presence of large vacuoles.