Sentence examples for uncontrolled accumulation from inspiring English sources

Leukemia is a malignant disease characterized by the uncontrolled accumulation of abnormal white blood cells.

The uncontrolled accumulation of these molecules in wine leads to sensorial defects that compromise wine quality.

However, while the ATP driving force module is effective for increasing product formation, uncontrolled accumulation of intermediate metabolites likely led to metabolic imbalance and thus to cell growth inhibition.

There is considerable evidence supporting the view that peri-implant diseases are infectious in nature and mainly linked to an uncontrolled accumulation of bacterial plaque biofilms [1].

Thus, one signaling cycle or constant action of NF-κB from LMB or CHX, respectively, induced opposite functional consequences: premature termination or uncontrolled accumulation of target gene transcripts.

However, misregulation and persistence of myofibroblasts can lead to uncontrolled accumulation of matrix proteins, tissue stiffening, and ultimately disease.

However, uncontrolled PMN accumulation can lead to injury to host tissue and cells.

Mutations in the β-catenin gene (CTNNB1) itself also leads to uncontrolled protein accumulation (Morin et al, 1997).

However, uncontrolled neutrophil accumulation within the lung after this early beneficial window markedly increases pulmonary pathology by consolidation of alveolar space, release of damaging neutrophilic contents [reactive oxygen species (ROS), proteases, etc.] and release of products that contribute to sterile tissue inflammation processes.

It is a widely accepted view that uncontrolled proliferation and accumulation of contractile myofibroblasts underlies the pathogenesis of DC [ 3].

Among oncohematological diseases, acute lymphoid leukemia (ALL) and acute myeloid leukemia (AML) are characterized by the uncontrolled production and accumulation of blasts that can lead to death.