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At a battlefield hospital in Afghanistan, Mitch underwent an emergency procedure called a decompressive craniectomy, where surgeons removed a 13-in (33-cm) piece of his skull to help make room for uncontrollable brain swelling.
Traumatic brain injury (TBI) patients with clinical and tomographic signs of intracranial hypertension and brain herniation due to uncontrollable brain swelling for whom decompressive craniectomy was indicated and in whom transcranial Doppler (TCD) ultrasonography had been performed were prospectively enrolled.
The observation that the differences in mortality were even higher after exclusion of the patients with traumatic brain injury supports this assumption, because this group of patients was at risk because of uncontrollable brain oedema and not hypocoagulability.
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Other major exclusion criteria were a history of hemoptysis, a history of peptic ulcer within the past year, severe or uncontrollable comorbidities, brain metastases, massive pleural/pericardial effusion or ascites, regular use of anticoagulants (≤325 mg per day of aspirin was permitted), or concomitant malignancy.
She added, "Persistent seeking and using drugs are human actions not uncontrollable products of brain activity and the literature on the responsiveness on such actions, even in the presence of addiction-related brain changes, provides overwhelming support for the ability of addicts to change their behaviour in response to incentives".
She added, "Persistent seeking and using drugs are human actions not uncontrollable products of brain activity and the literature on the responsiveness on such actions, even in the presence of addiction-related brain changes, provides overwhelming support for the ability of addicts to change their behavior in response to incentives".
Uncontrollable Bleeding: A Brain Surgeon's Nightmare.
On the other hand, it is reasonable to accept the occurrence of cerebral hyperemia in patients with uncontrollable increased ICP and brain herniation, as seen in our series.
Measuring of the other physiological variables also requires the use of invasive cerebral and jugular venous catheters, as well as time-consuming procedures that are difficult to justify in patients with neurological deterioration and evidence of uncontrollable intracranial hypertension and brain herniation.
Microinjection of a 5HT 1antagonistst (WAY 100635) into the spinal cord before intact rats received uncontrollable stimulation blocked the brain-dependent protection of spinal cord neurons.
This trajectory consistently included the following elements: trauma, including impacts of trauma; a lack of support; substance abuse to mask the pain, and as a reason for violence; and a brain snap, or uncontrollable anger and violence; resulting in incarceration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com