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In this manner, effectiveness as well as potentially uncommon adverse effects of statins can be examined over extended periods of time in "real-world" populations [ 52].
Equianalgesic Table of Opioids adapted from Levy Opioids have common and uncommon adverse effects (Table 3).
The scientific literature gives very little guidance in this question as trials and meta-analyses are not powered to quantify serious but uncommon adverse effects.
Myopathy, and the more serious rhabdomyolysis, are important, if uncommon, adverse effects (0.1/1000 people treated for a year or less).
Phase I trials are generally designed as pharmacology studies; phase II trials are therapeutic exploratory investigations; phase III trials are assessments of the effectiveness of the new intervention; and phase IV trials are investigations into uncommon adverse effects of the new intervention [ 134].
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She was transitioned to comfort measures only and died 12 days later.MIE is an uncommon adverse effect of treatment with metronidazole that characteristically affects the dentate nuclei but may also involve the brainstem, corpus callosum, subcortical white matter, and basal ganglia.
Transient hypopigmentation and hyperpigmentation was an uncommon adverse effect.
Serious but uncommon adverse side effects may not be recognized until drugs are used in large populations (4 ).
1 2 3 Although diagnostic radiography and other radiological imaging procedures to the abdomen and pelvis of pregnant women are uncommon, potential adverse effects of exposure to radiation in early life remain a concern with the growing use of computed tomography scans and other recent types of higher dose imaging procedures.
Adverse effects were uncommon.
Adverse effects were uncommon suggesting safety in short-term use of rofecoxib and naproxen sodium.
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