Although the reasons for some of these discrepancies remain unclear, variations in somatic cell sources, virus quality and infection protocols are known variables in reprogramming [16].
Whether 25(OH D directly influences absorption is unclear, variations in 25(OH D levels are not associated with significant variations in 1,25(OH)2 D levels, and in osteomalacia, calcium absorption may be profoundly diminished despite normal or elevated levels of 1,25(OH)2 D [ 6].
It is also unclear whether variation in NHS service provision contributes to variation in outcome.
This could be a reason for the observed unclear seasonal variation.
While the phenotypic changes were fairly minor and their causes and/or effects unclear, greater variation could be expected between the products of chemically-defined culture systems.
Thus, it is unclear whether variation in levels of physical activity during pregnancy is (either beneficially or detrimentally) related to long-term cardiovascular health in offspring.
However, as these data represent 15 individuals from each of the three populations (Aripo, Paria, and Quinam) grouped together during analysis, it is unclear if variation in λmax is attributed to individual and/or population-level differences.
Females show preferences for males of high quality (Ilmonen et al. 2009), and female mate preferences can provide indirect benefits (Drickamer et al. 2000), but it is unclear how variation in male quality affects female MMM or the consequences of multiple paternity.
The reasons for differences in outcomes are unclear, but variations in medication adherence may play a role, because medication adherence is essential to achieving better outcomes.
Severe short-term sodium restriction or extreme sodium loading may alter glucose tolerance and insulin resistance in patients with hypertension, but it is unclear whether variations in sodium intake within the clinically observed range affect glucose tolerance.
