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A review in Variety was negative, noting specifically that the "stilted acting, asides to explain characters and motivations, and a repetition of effects lose the initial impact" and an "unclear progression and plodding direction give [the film] an old-fashioned air".
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Ray Barnholt of 1UP.com, Ryan Davis of GameSpot, Micah Seff of IGN, and Gus Mastrapa of X-Play all labeled the often-unclear progression presented to the player as "frustrating" and "tedious", requiring an excessive amount of patience.
Although the mechanism of the resistance to mTOR inhibitor is unclear, disease progression after initial everolimus treatment may be explained by evolving progression mainly due to proliferation of the remnant resistant subclones.
Another problem was the unclear character progression at the end of the story missions.
In this paper, respondents spoke of emigrating for professional reasons as a result of poor working conditions, a lack of respect, unclear career progression and poor practice environments.
Although the causal mechanisms for the pathogenesis of PAH remain unclear, the progression of PAH is the result of pulmonary arterial endothelial dysfunction leading to an imbalance between key pulmonary vascular mediators, such as decreased nitric oxide (NO) and prostracylin and increased endothelin-1.
"Within an organisation it's often very unclear what the progression structures are.
Although the association with IgG4-related disease and colorectal disease is unclear, the tumor progression was atypical for rectal cancer.
Even higher incidence of unclear early radiographic progression at the first postradiotherapy imaging was reported [ 7].
The role of CB1/CB2 receptors expression and ratio is unclear in HCV progression.
It remains presently unclear whether disease progression in colorectal carcinoma (CRC), from early, to invasive and metastatic forms, is associated to a gradual increase in genetic instability and to a scheme of sequentially occurring Copy Number Alterations (CNAs).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com