The relationship between current use of exogenous hormones and meningioma remains unclear, limited by the small numbers of patients currently on oral hormone medications and a lack of hormone receptor data for meningioma tumors.
In addition, although the complete role of Tetherin in mammals remains unclear, limited data show that Tetherin can (at least) mediate a specific feedback mechanism to turn off interferon production by plasmacytoid dendritic cells [8], [47].
Blast appears to produce a distinct pattern of TBI, 15, 27 although the mechanism by which blast injury damages the brain remains unclear, limiting our ability to identify those patients at high risk of pituitary dysfunction.
For example, the extent to which individual articles described the results of independent studies was often unclear, limiting our ability to report the results of our review with studies as the units of analysis, and rather requiring articles be the unit of analysis.
Likewise and more importantly for its application as an animal model, the genomic and functional conservation of lipid metabolism from C. elegans to humans is unclear, limiting C. elegans' utility for in depth exploration of the fundamental mechanisms of lipid metabolism and human metabolic diseases.
However, the detailed mechanisms of borrelidin against ThrRS, especially borrelidin binding site on ThrRS, are still unclear, which limits the development of novel borrelidin derivatives and rational design of structure-based ThrRS inhibitors.
Owing to that concrete is a severely heterogeneous material at micro scale, the relationship between stress wave parameters and microstructure of concrete such as pores and preexisting cracks in concrete is still unclear, which limits the generalization of monitoring system in different concrete structures.
However, the fracture morphology and propagation law of it are still remain unclear, which limits the development and application of it.
Finally, the median joining network (Fig. 2A), outlined unclear genetic limits among both Prunus species.
For example, the stability of maternal cognitive style throughout the child's life was unclear, which limits our understanding as to when it influences the child.
