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In response to increasing use of lumbar fusion for improving back pain, despite unclear efficacy, particularly among injured workers, some insurers have developed limited coverage policies.
In conclusion, current literature data evidence still unclear efficacy of pharmacological treatments for BED.
Drug combinations that do not have ATC codes for the corresponding drug components and combinations with none or unclear efficacy were discarded.
15 16 Such findings highlight the need for classification criteria with improved performance characteristics, with higher specificity likely to be favoured in order to ensure that individuals enrolled into trials for treatments with unclear efficacy and safety truly have gout.
Out of 221 HIV+ women who have received AZT during their pregnancy: 1/3 started at 34 weeks 1/3 received 2 weeks or less 1/3 started during labor which means that 2/3 of the patients received a suboptimal regimen with unclear efficacy.
Next, the expert panel performed a threshold identification exercise designed to assess the members' willingness to enrol 47 paper cases, based on having sufficient confidence that the individual has gout, into a Phase 3 randomised clinical trial of a new urate-lowering agent with unclear efficacy and safety.
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The weight-adjusted dose of buccal MDZ that would be sufficient to control seizures in this group has not been defined, and it is still unclear whether efficacy and safety of this dose would be dependent on age.
Although the cause-and-effect chain between surveillance and prevention measure compliance is still unclear, the efficacy of surveillance systems in the prevention of hospital acquired infections has been shown previously [ 36- 39].
It is currently unclear from efficacy, safety, tolerability or health economic perspectives whether mild or maximal ovarian stimulation (with cryopreservation of supernumerary embryos) is most beneficial (Fauser et al., 2005).
Although the exact nature of immune-incompetence in young children remains unclear, the protective efficacy of BCG against childhood TB indicates the lack of effective T cell-mediated immunity in them [64].
However, it remains unclear how therapeutic efficacy and safety might vary over a range of different warfarin or LMWH doses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com