Factors impeding spread included resource constraints, unclear responsibility for funding and accountability for implementation, and pre-existing ways of providing palliative care.
How that can be achieved, given current budget constraints, is unclear.
We close with an analysis of what it means to design within a rapidly changing technical environment, one where the capabilities and constraints are unclear.
How disordered regions are maintained at high abundance in the proteome and across taxa, despite apparently weak evolutionary constraints, remains unclear.
Although the reasons why screening has not been widely implemented are unclear, they include time constraints, lack of reimbursement, stigma (on the part of both the patient and the physician), and financial barriers to effective treatments (e.g., psychotherapy and antidepressant agents).
In instances where data were unclear and/or incomplete, time constraints prohibited contacting authors to clarify data and citation tracking for subsequently published studies was not feasible.
It remains somewhat unclear if short-run credit constraints or the long-run economic situation are more important determinants.
However, it remains unclear to what extent fiscal constraints, a dubious return on the investment dollar, or unevenly distributed benefits of the project influenced decision makers regarding the desire to complete the project, or not.
Additionally, it is unclear whether teachers incorporated developmental constraints, or other lesser-known non-adaptive factors (see Gould 2002), into their teaching in all the biology classes or if it was only found in the evolution course.
Even in the absence of institutional constraints, it is unclear whether the use of prescribed fire would benefit sage-grouse.
A number of challenges were also identified which related predominately to budgetary constraints, staff turnover, unclear governance structures, lack of ongoing high level leadership and inadequate communication between the partnering organisations.
