Sentence examples for unclear altered from inspiring English sources

Although the details are yet unclear, altered replication origin firing may be the underlying cause behind oncogene-induced replication stress [ 65].

The reasons for extra-articular Y-90 activity in the three patients in our study also remain unclear, although altered needle/joint capsule positioning after aspiration of synovial fluid is likely given that all three patients with extra-articular Y-90 activity had the procedure performed on the knee without fluoroscopic guidance.

It remains unclear how altered functional activity can lead to the morphological disarray observed for FHC hearts.

The underlying cause for our findings is unclear, but altered OSS behavior in both mGluR5 KO and Het mice suggests that even subtle variation in mGluR5 expression is capable of altering reinforcement behavior in this paradigm.

Hence, aging may impact alloimunity via multiple effects, although it is unclear whether altered cellular alloimmunity with aging is due to impaired priming by dendritic cells (DCs) or due to defective intrinsic T cell function.

It was unclear if altered gene expression was caused by direct TH action, or due to downstream effects in the liver resulting from an altered developmental trajectory.

The mechanism of anaemia's purported impact on outcome is unclear, although altered metabolism in brain tissue that is sensitive to reduced oxygen delivery is plausible.

However, lacking a systematic study of the frequency and biological effects of non-synonymous variants, it remains unclear which altered functions are meaningful markers of clinical pathogenicity.

Although at the present time it is unclear whether the altered gene expression resulted in permanent alterations, the gene targets and molecular pathways identified at 72 hpf support a molecular basis for alterations of neurite growth and synapse formation and function that have been observed in previous studies.

It remains unclear whether these altered plasma concentrations are related to the diabetic state or presence of obesity.

In addition, it is unclear whether significantly altered gene expression changes are causes or consequences in the development of diabetic cardiomyopathy.