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But the notion that extreme heat will become a fact of life for Europeans does not necessarily imply an unchecked increase in related deaths.
It has long been known that in neurons and other cell types an unchecked increase in cytosolic Ca2+ concentration ([Ca2+]c) can trigger apoptosis [14] and likewise, agents able to release Ca2+ from intracellular stores have been shown to be pro-apoptotic [15].
Similar(58)
The CBO acknowledges that "Unchecked increases in greenhouse-gas emissions" would "probably reduce output over time, especially later in this century".
The range of deleterious effects that have resulted and may yet result from unchecked increasing climate change are indicative of the profound threat that confronts our way of life (McFarlane 2010).
The alterations in [Ca2+]c disrupt Ca2+ homeostasis, and unchecked increases in [Ca2+]c can trigger apoptosis through the activation of processes in the cytoplasm (e.g., abnormal activation of calpain or phosphatase calcineurin), activation of ER resident caspases, or mitochondrial dysfunction due to Ca2+ overload.
The upward trend in the prevalence of childhood and adult obesity indicates that these costs unchecked will increase over time.
This unchecked growth will likely cause it to produce nitrogen, but it will also consume other nutrients at increased rates.
The period of unchecked growth is ending.
Unchecked, the increasing prevalence of obesity seen in Europe, North America and emerging economic areas will be likely to lead to an increase in the incidence of some cancers.
Left unchecked, the increasing prevalence of overweight and obesity in Ghana will exacerbate PIH levels in Ghana.
Thus, it is possible that mosquitoes with AaegPTEN knockdown may have unchecked ovary growth and an increase in the number of ovarioles.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com