The question is how it has changed relative to some unchanged-role-of-government baseline.
However, the expression of mPGES-1 and COX-1 remained unchanged indicating a role of these enzymes in the chronicity of these diseases.
Sputum IL-17 was also markedly attenuated by inhaled corticosteroids, but the sputum neutrophil count was unchanged, questioning the role of IL-17 in persistent neutrophilic airway inflammation.
Yuasa et al. reported that mRNA levels of PACE4 (paired basic amino-acid-cleaving enzyme 4), a member of PCs family, increased significantly during myogenesis, whereas the expression of furin and PC6 remained unchanged, highlighting a role of PACE4 in myoblast fusion.
LacZ mRNA from PZU MEFs also exhibited a similar elevation upon serum stimulation, whereas LacZ mRNA level from the PMZU mice remained unchanged, again suggesting a role of E-box in coordinating cell cycle progression and p53 expression.
Of course it has risen — we have a growing economy (usually) and a growing population, and you expect spending to rise even if the role of government remains unchanged.
Our own observation, which shows that the RecD subunit adds to the overall stability to the RecBCDPs complex in P. syringae (Pavankumar TL and Ray MK, unpublished observation) also supports that the subunits of RecBCD complex have coevolved but independently in different groups keeping overall role of the enzyme unchanged in bacterial cells.
Their activities were both lost by digestion with trypsin, but remained unchanged by oxidation with periodate, suggesting the role of the protein portions in their molecules.
This suggests an important role of E-cadherin in the unchanged histopathophysiology and maintenance of epithelial tissue structure [ 22].
Furthermore, the elevated mitochondrial function and unchanged mitochondrial structure provide additional evidence of the prominent role of HBOC in mitochondrial preservation.
These data in accordance with the unchanged mossy fibres of Dsp mutants suggest a Dsp-independent role of Bcl11b in learning and memory.
