DANITA EDWARDS, the N.C.A.A.'s vice president for public affairs, said: "I think right now we're dealing with such a level of uncertainty regarding anything that could happen, that we're certainly paying attention.
Investors are wary of the Medicare drug benefit, said SG Cowen, given uncertainty regarding price discounts that may be demanded by the government.
Similarly, due to the case-mix in many trials there is also some uncertainty regarding the families that would most benefit from this form of treatment.
Although feeding practices likely play a role (Koletzko et al. 2009; Worobey et al. 2009), there is considerable uncertainty regarding other factors that may program this rapid infant growth.
The posterior distribution summarises the uncertainty regarding unknown parameters that remains after combining our a priori knowledge (if any) with the evidence contained in the data via Bayes' theorem (Gelman et al., 1995); in other words, it is the probability distribution of the model parameters given the data (Kirkwood and Sterne, 2003).
Here, we describe an approach that can be used when both the clinical and in vitro data are available, but there is uncertainty regarding a particular parameter that is inherent to the PBPK model.
Service providers and former inmates indicated that uncertainty regarding release dates meant that discharge summaries were not always written and a week's supply of medication not always provided to inmates on release.
Although a great diversity of specific disease concepts exists there is much uncertainty regarding the biological mechanisms that could justify them.
However, such estimates are subject to parameter uncertainty regarding the input variables, that is, all drug and non-drug costs and health outcomes.
This analysis illustrates the range of uncertainty regarding the probability that a patient with a non-HSIL anal cytology result actually harbors HSIL changes if that patient was selected from a population with known HSIL prevalence.
