We calculated the two-dimensional BGHS depths considering the 25% uncertainty demonstrated in the "Uncertainty in BSR-derived heat flow" section.
For both scenarios, the most stable measure is based on the symmetrical uncertainty, demonstrating that it is possible to accurately classify the PCG and EEG signals using around the 15% of the information given by each t f representation.
The numerical simulations of the optimal control in the presence of parameter uncertainty demonstrate the robustness of the optimal control: the main conclusions of the optimal control remain unchanged, even if inevitable variability remains in the control profiles.
Key features of BEPU can be summarized as: procedures for nodalization development, code and nodalization validation, addressing the scaling issue, evaluation of uncertainty, demonstrating the analyst qualification, integrating the needs from licensing, coupling of codes from different disciplines and validation of the related software, considering the latest established findings from R & D.
The uncertainty demonstrated by the divergence in expert opinion can be described by fitting appropriate probability distributions for probabilistic sensitivity analyses.
The probabilistic approach to analyze the uncertainty demonstrated that the laparoscopic procedure was close to clear dominance over open surgery and cost-effective at a WTP below the current threshold set by NICE.
This conclusion is supported by the decision uncertainty demonstrated by the sensitivity analyses; thus, the state coverage of this drug for both treatment-naïve and refractory/relapsed population remains a possibility to be argued.
The geostatistical map presents estimates of these serological indicators beyond the sampled locations, allowing evidence-based intervention targeting to take place beyond sampled clusters, along with estimates of model uncertainty demonstrating settings where further data may be needed for decision making.
Our study, in spite of its limitations and uncertainties, demonstrates the importance of a quantitative holistic approach in linking human and natural systems and estimating tradeoffs between economic benefits and environmental quality.
The simulation results under the nominal conditions and parameter uncertainties demonstrate the superior performance of the proposed controller.
