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The association with the UKPDS risk calculations also must be interpreted with caution since the risk engine is not validated for a diabetes duration of >20 years and has an uncertain validity for patients with established cardiovascular disease, although only patients with acute cardiovascular disease were excluded in the original UPKDS study [ 35].
Surgical adverse event (AE) monitoring is imprecise, of uncertain validity, and tends toward underreporting.
Thus their findings reflect the limited scope, quantity and usually uncertain validity of the available evidence from the trials available.
Another limitation of our study is the uncertain validity of the specific diagnosis of dementia using record linkage.
Some of these decisions are based on data of uncertain validity, unknown reproducibility and unclear appropriateness.
Age was not included in the regression models due to the variable's uncertain validity.
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Here's what we know so far: A well-connected company with questionable finances and a research proposal of uncertain scientific validity has received favorable treatment from CIRM.
Hence, the classification of our population into different seasonality groups could be argued to be of uncertain clinical validity.
The EAC concluded the technology had potential to improve detection of AF, but the three studies had uncertain external validity.
In addition, many previous studies on job strain and depression have applied outcome measures with uncertain diagnostic validity, for example self-reported symptoms.
However, octa-BDE, although detected at a high concentration (see Table S4, Supporting Information), was excluded from the present analysis because of the uncertain method validity for this congener.
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