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Last year, the Advisory Council on the Misuse of Drugs (ACMD) suggested that new drugs of uncertain harm might be put into a holding class – such as the "class D" approach adopted by New Zealand several years ago to deal with BZP with some success.
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Thus in an everyday nuisance suit between private parties over sewage and odors, the key question involves the choice of remedy for future and uncertain harms.
However, if we make the cost benefit trade-off between certain death and the chance of a lingering life of poor health, the precautionary principle (which skews this trade-off against uncertain future harms) should itself be applied with caution.
But rarely has there been an attack that had such uncertain potential to harm a candidate in a primary but such clear potential to harm him in the general election.
We argue that lying in professional contexts share three characterizing features: (1) the gain from the dishonest behavior is uncertain, (2) the harm that lying may cause to the other party is only indirect and (3) lies are more indirect lies by action or written statements.
She said she doesn't believe the college's uncertain fate will harm its reputation or her job prospects.
Researchers told us that IRBs frequently express concerns that disseminating uncertain data may harm human subjects.
41 Targets of covert aggression in middle childhood are likely to remain unidentified when there is uncertain evidence of harm and the source is not clearly identified, for example, when the in-group of the bully participates in a lie.
In the internal cohort crossover analysis that is, analysing outcomes before and after treatment in the same population the differences in incidence did not reach statistical significance, making the estimated number needed to harm uncertain.
For example, some writers suggest that it may be unreasonable to expect even fully informed citizens to take on what they depict as the burdensome task of decision making for cancer screening: weighing up uncertain benefits and harms, about which experts disagree [ 44].
The strength of recommendation will be considered weak when the balance of benefit and harm is uncertain (quality of evidence is low or very low), or when values and preferences are uncertain or when much higher costs are envisaged.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com