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The Trial-Journal Pipeline consists of randomized clinical trials designed with the marketing departments to produce evidence that their drugs are more effective and safer than unbiased trials would show.
We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials.
As the first step in the development of a knowledge translation strategy to address the reduction of bias in pediatric RCTs, the objective of this study was to determine and describe the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials, with an emphasis on the Canadian context.
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You might get arrested, put in jail and then subjected to a completely fair and unbiased trial.
"This is not happening until the U.S. government stops politicizing Edward's case and offers him a fair and unbiased trial".
In this hypothesis we try to suggest a new blinding protocol acting as a gold standard for design and conduction of unbiased clinical trials.
Only 12 studies of 1335 abstracts screened fulfilled Cochrane inclusion criteria for well-conducted unbiased clinical trials (Pfeffer et al., 2012; summarized in Table 1).
Then we can discuss whether these benefits are likely to be superior or equal to those of popular alternatives, even though randomized unbiased comparative trials are not available.
George F. Koob, the director of the alcohol institute, said the trial will be immune from industry influence and will be an unbiased test of whether alcohol "in moderation" protects against heart disease.
The validity of systematic reviews and meta-analysis is depending on methodological quality and unbiased dissemination of trials.
The validity of systematic reviews and meta-analysis depends on methodological quality and unbiased dissemination of trials.
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