Sentence examples for unbiased sequencing of from inspiring English sources

Here, we explored human small RNAs by unbiased sequencing of RNAs with sizes of 19 40 nt.

Here, we explore small RNAs by large-scale unbiased sequencing of RNAs with sizes of 20 40 nt.

If DNA library preparation protocols and sequencing machines were able to produce error-free and unbiased sequences of sufficient length the task of variant calling would be easy.

In 2008, an unbiased sequencing study of human small RNAs (19 40 nucleotides) led to the observation of specific processing and the accumulation of small RNAs originating from well-characterized non-coding RNAs including snoRNAs [16].

Considering this, unbiased sequencing surveys of tumor transcriptomes or genomes are expected to reveal mutations in these commonly affected cancer genes as well as many novel mutations in genes with no previous implication in cancer.

It further highlights the interest of unbiased sequencing technique, which allows investigating the implication of the same gene in different modes of inheritance.

However the sequencing and data processing burden is still the bottleneck for widespread use of unbiased sequencing.

Here, we define the unbiased sequence selectivity of the tru pathway with the heptapeptide series.

Interestingly, one group [ 49] has reported that their unbiased sequence interrogation of the genuine chromatin binding sites suggests that direct ER binding requires the presence of foxa1 binding in close proximity, as knockdown of FoxA1 expression blocked the association of ER with the chromatin and estrogen induced gene expression.

Such abundant read sequencing enabled us to obtain almost full-coverage contig sequences for the viral segments using de novo assembly, suggesting the importance of this result in terms of being able to evaluate uncharacterized emerging infectious agents using an unbiased sequencing technique at the outbreak of a pandemic.

To elucidate the genetic basis and architecture of SUDEP, we used an unbiased sequencing approach based on whole-exome sequencing data.