In all experiments, the noise estimation in the decomposition levels was done using the heuristic variant of the Stein's unbiased rule.
Immunopositive cells were counted using the optical-fractionator method with the dissector principle and unbiased counting rules.
We assess multivariate QUEST DTs with unbiased classification rules and linear discriminant node models for integrated vegetation mapping and change detection.
Six nigral sections (every sixth section) from each rat brain were chosen (ranging from approximately 4.5 to 6.0 mm posterior to bregma[24]) and the cells were counted bilaterally in a blinded fashion using unbiased counting rules.
If one stringently follows the unbiased counting rules and has a consistent labeling protocol, it is striking how quantitatively reproducible the results are from one EM grid to the next, and from experiment to experiment by this simple approach.
Cell profiles were counted at a final screen magnification of × 1024 using a 2D counting frame and a simple, unbiased counting rule (Gundersen, 1977).
Uninfected cells were sampled using the forbidden line unbiased counting rule applied to quadrats positioned SUR (4 quadrats per micrograph, 0.0019 mm per quadrat; n = 83 cells) on the same set of images.
Efficient in silico models can be built that integrate current heterogeneous genome-editing data to derive unbiased sgRNA design rules and identify key features for improving sgRNA design.
Sanctions can be difficult to enforce where management and monitoring capacity are poor, and where cultural, kinship or hierarchical systems prevent the unbiased application of rules and regulations to all health workers.
Notably, the rule 'CSF2RB high in Rappearedred in the independently established rule sets of all analyzed cohorts (rule set 'Jena', position 17; rule set 'Berlin', position 28; rule set 'Leipzig', position 1; and, remarkably, rule set 'Total', position 3), again underling the validity of the completely unbiased procedure of rule set generation.
