When the current speaker corresponded to the worm's bias, movements in the positive direction were 25% steeper than the unbiased worm, and movements in the negative direction were 25% less steep.
Conversely, when the current speaker corresponded to a candidate not favoured by a worm, movements in the positive direction were 25% less steep than the unbiased worm, and movements in the negative direction were 25% steeper.
In addition a thermally averaged NEB method has been implemented to produce an unbiased view of the movement of atoms as the system evolves along the reaction path.
Given the extreme complexity and quickly changing nature of this behavioral phenotype in mice we elected to perform unbiased computerized assessment of abnormal movement behaviors in locomotor activity chambers, rather than just simply applying ethological scoring approaches developed for other manifestations of abnormal behavioral activation, such as stereotypies and dyskineisas.
Few have explored the relationship between neuropathology and gait, movement disorder or functional disability in an unbiased sample of the ageing population among whom a sub-clinical threshold of such symptoms is common[ 15].
Similar studies have been performed by using unbiased MD simulations to deepen aspects related to interdomain movements in polyketide synthases [ 44] or elastic network models to gain insights into the AcrAB-TolC complex [ 45].
However, given that these studies were conducted using ChIP-seq, we considered that they may not provide a completely unbiased view of the role of chromatin architecture in regulating Pol II movement.
They assumed that this class of retrogenes replaced the ancestral functions of the parental gene, and reported that these retrogenes, although mostly originating from movement out of the X chromosome, showed female-biased or unbiased expression.
But there is hope, too: that the protest will become a movement for a fair trial, and for a final, definitive and unbiased account of what happened in 1971; for the strengthening of secular, progressive politics in Bangladesh.
Thus, we elected to employ this model to perform an unbiased screen of putative TAAR1 ligands and monoamine metabolites for potential actions on movement control.
