Sentence examples for unbiased characterization from inspiring English sources

Because of this, accurate and unbiased characterization of dendritic spine structure is vital to our ability to explore and understand their involvement in neuronal development, synaptic plasticity, and synaptic failure in neurological diseases.

Here, we developed a novel split-ubiquitin membrane yeast two-hybrid (MYTH) technology called CHIP-MYTH, which allows the unbiased characterization of interaction partners of full-length GPCRs in a drug-dependent manner.

Therefore, it is considered a powerful tool for the unbiased characterization of genotypes and phenotypes with application in multiple areas, such as evaluation of genetically modified organisms [10] [12], functional genomics [13] [17], responses to environmental factors [18] [23], metabolic engineering [24],[25], and quantitative genetics [26] [30].

In contrast, full re-sequencing surveys, in which the sequence of a genomic segment is determined in each individual in the sample, allow an unbiased characterization of multiple aspects of genetic variation and are suitable for standard methods of population genetics analyses.

Here we review some methodological reasons for these inconsistencies, and take them into account to provide an unbiased characterization of mtDNA and NRY variation in chimpanzees, one of the few mammalian taxa where males routinely remain in and females typically disperse from their natal groups.

A complete and unbiased characterization of the transcriptome dynamics of spermatogenesis is, however, still lacking.

In conclusion, this is the first unbiased, functional characterization of the urinary proteome using serine hydrolase ABPP.

The preceding section provided an overview of unbiased functional characterization of the regeneration-associated genes at the global, transcriptome-wide level.

The ubiquity of splicing, especially in humans, has been revealed by next generation sequencing methods that allow unbiased, global characterization of splicing in many cell and tissue types [ 27, 28].

Moreover, methylated DNA immunoprecipitation (MeDIP) may be useful for unbiased detection and characterization of DNA methylation patterns [ 9].

Serial analysis of gene expression (SAGE) is a comprehensive profiling method that allows for global, unbiased and quantitative characterization of transcriptomes [ 6, 7].