Population estimates remained essentially unbiased with changes in the detection probability.
This finding builds on growing evidence that maternal adversity during gestation induces unbiased epigenetic changes in offspring genome.
On the other hand, if sample sizes are large, variances can be estimated separately and one should focus on unbiased fold changes.
The real benefit of SDT analyses is that they allow an unbiased evaluation of change deafness manipulations.
We review recent developments in methods and designs that aim to integrate sources of error to provide unbiased estimates of change in biological diversity and to suggest the potential causes.
Global rating scales are typically correlated with the patients' present status and are not an unbiased measure of change.
Bayesian skyline plot analyses use data from a single population to provide an unbiased estimate of changes in Ne through time, and thus are a powerful means for estimating past population growth patterns when the nature of the growth (e.g. exponential or constant) is unknown [32].
Quantitative null models (e.g. Patefield's algorithm) control for sampling bias, abundance and diversity, and are thus important for the unbiased interpretation of changes in network metrics.
Despite robust transcriptional changes, unbiased quantitative proteomics detects production of only a few critical anti-apoptotic proteins against a background of general translation inhibition.
Later on, statistical tools [ 3] were added to this software package to get an unbiased overview of changed pathways or processes.
