The phrase "unbalanced function" is correct and can be used in written English
It can be used to describe a function that does not have equal input and output, or if a particular function is highly imbalanced. For example, "The unbalanced function of the machine resulted in it breaking down after a few hours of use."
In Figure 2(c), for unbalanced function based MDR, the TNs are not always higher than the TPs.
In contrast, we demonstrated that our proposed unbalanced function based MDR is suitable for an imbalanced data set.
The MDR method was briefly introduced and the unbalanced function based MDR method was explained in detail as follows.
The effect of IFIT4 on monocyte differentiation into DCs was suggested to be partially responsible for this unbalanced function of monocytes and DCs in SLE [ 2].
Here we provide an example to show how the unbalanced function based MDR works (see Supplementary File in Supplementary Material available online at http://dx.doi.org/10.1155/2015/454091).org/10.1155/2015/454091
The unbalanced function based MDR model can explore the epistasis network of SNPs AGT, ACE, and AT1 R of RAS genes and identify strongly significant hypertension association.
Surprisingly, a high (>2) FcopyA copy number was also associated with susceptibility to SLE (Table 2), suggesting that the unbalanced functions of FCGR3A (both a deficiency and an overload) play a role in the pathogenesis of SLE.
It is currently known that the relationships between the different parts of the nervous system are mediated by neurotransmitters and that their disorders lead to unbalanced functioning of certain structures and to the development of well known diseases.
Furthermore, the use of an unbalanced weighting function in a sequential Bayesian positioning system might also lead to such multimodality.
Obstruction of the upper airways forces the patient to breathe through the mouth, and in addition to OSAS, these factors cause oral dysfunction, such as lip incompetence, low position of the tongue in the floor of the mouth, tongue thrust, and may lead to unbalanced muscle and function [32] disturbances in swallowing, mastication, speech [34], and stability of occlusion [35].
Hence, the obtained results support a multimodal dopamine-adenosine approach for PD management: selectively targeting the D2R-A2AR oligomerization status via combined pharmacotherapeutic strategies could restore the unbalanced D2R-A2AR oligomer function associated with PD.
