As a corollary, the study provides a useful paradigm to study the voluntary control of unavoidable action.
However, to solve these questions, it is unavoidable to continue the studies for additional follow-up time and the organisation of large Phase IV studies, some of which are already in place.
To this end, Ethics Committees licensed the study since it was unavoidable to investigate the impact of apoptosis on survival without 7-day survival as an endpoint.
The logistics of patients having to attend an additional clinic within the intervention group resulted in the loss of patients due to illness and bereavement which were unavoidable losses to the study and two due to forgetting to attend.
Finally, we present a simple and easy to implement parallelisation scheme, as high performance computing is unavoidable when studying large scale problems involving several thousands of simultaneously deforming bodies in highly turbulent flows.
Small sample size for individuals naturally surviving infection (i.e., without interventions such as fungicidal treatment) was unavoidable for this study due to this species' high-susceptibility to Bd; only two of 60 frogs infected with Bd survived the original experiment (Langhammer et al. 2013).
125 346 347 While some amendments may be unavoidable, a study of pharmaceutical industry trials found that according to the sponsors, a third of amendments could have been prevented with greater attention to key issues during protocol development.
Due to the inclusion of questionnaires on service use and housing trajectories (unavoidable given study objectives), blinding of interviewers was infeasible.
Unfortunately, these were unavoidable in this study because they had to be adopted from the EFSA report [ 8, 9] that was under scrutiny.
However, such heterogeneity was not surprising because of unavoidable variations in study population and distinct adjustments across studies.
