When cuts are unavoidable, targeting has been the traditional way to go.
This phenomenon should be taken into account when it is unavoidable to target the repeat regions.
- However, nicotine toxicity due to unavoidable off target effects in the neural system precludes its wide use and urges a search for non-toxic nicotinergic drugs that can mimic healing effects of nicotine in mucocutaneous wounds.
However, mTORC1 inhibition per se can reduce the mRNA expression of mitochondrial genes and compromise the function of mitochondria in cultured muscle cells, implying that defects in bioenergetics might be an unavoidable consequence of targeting mTORC1 in vivo.
Of course, the existence of false positive targets is unavoidable.
Where food subsidies are unavoidable, they should be temporary and targeted on the poor.
"Do not go out of the village wearing TeamGB kit or carry anything of value unless absolutely unavoidable – this makes you too big a target for theft/crime," it adds.
However, unavoidable recombination limited precision of selection between target gene and markers (Andersen and Lubberstedt 2003).
Although a target altitude was set fluctuations were unavoidable and actual altitudes were also recorded via a laser altimeter.
When a large TPSA is unavoidable because of the nature of the protein target, decreasing the molecular size and side chains may help them pass into the brain.
