However, because the majority of the integration was randomly located in the genome, the risks of the random integration were unavoidable for these methods [ 10– 10].
Each method carries unavoidable limitations and setbacks of its own.
To fill the void of controlling unique variable, the employ of monitoring profiles method is unavoidable.
Although unexpected, it is most likely a result of mixing the cytosolic and mitochondrial pools of redox cofactors which is unavoidable with the extraction method used.
Some arbitrariness in the choice of the methods is unavoidable, but we feel that the current selection covers the spectrum of methods currently available and attractive for microarray studies reasonably well.
This rationale reduces, as much as possible, the unavoidable approximations introduced with any method of data interpretation.
This ratiocination leads us to compare the plan and film results with unavoidable errors by a traditional method based on human observation.
Without considering the GMS, an analysis may falsely conclude that certain regions of the genome do not undergo mutations, while in fact through an unavoidable limitation of the resequencing method, the experiments have no power to measure those variations.
However, in polyploid species, the production of multiple PCR products is unavoidable even when using these methods.
In light of the range of uncertainties and the unavoidable limitations inherent in modelling methods, we present our findings as exploratory and aim to provide qualitative insight into decisions that countries will be facing in the coming years regarding HPV vaccine implementation.
