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Decoron presents in solution and crystals as a dimer, in which the putative binding sites on the concave face are buried, unavailable to interact with other ligands.
It is expected that interactive domains on the surface of αB crystallin can be occupied by tubulin subunits when the ratio of αB crystallin∶tubulin is small and αB crystallin is unavailable to interact with other αB crystallin subunits to form a complex.
An important consideration is that adenosine is rapidly transported into red cells via the equilibrative nucleoside transporter and this makes the adenosine unavailable to interact with platelets.
The Rvb inserts, known to be involved in ring-ring interactions in dodecameric structures (Gorynia et al., 2011; López-Perrote et al., 2012; Torreira et al., 2008), face the core of SWR1, making them unavailable to interact with a second ring.
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These mapping results suggested that overexpression of FLAG-Imp- β1-N2 (1–650 aa) mimics the RanBP2 siRNA phenotype through the sequestration of endogenous RanBP2, making it unavailable to interact productively with full-length importin β1, thus causing the re-appearance of the enhanced chromosome segregation abnormalities.
For example, it is possible that the exofacial thiol targets of parthenolide are reduced on cancer cells, and thus are free to interact with the drug, but are oxidized on normal cells, thus unavailable for interaction with parthenolide.
You get to interact with people.
And I love to interact with that".
Now he has one to interact with.
"They want to interact with you.
Nick tries to interact with Cassandra.
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