The rapid reversal in the hepatitis B birth dose recommendations may have led to unanticipated disruptions in immunization delivery.
This outcome underscores the importance of designing vectors for site-specific gene insertion to avoid unanticipated gene disruption or gene activation.
21 Rapid uptake of a new technology may have unanticipated consequences, including disruption of the normal practices of medical education and patient care.
In summary, our data presented here reveal an unanticipated effect of esBAF complex disruption on replication timing and, by proxy, higher-order chromatin folding [ 10, 37, 38].
Disruption management in industrial areas consists in dealing with unanticipated events that get the plans deviate from their intended course.
All social changes are somewhat costly, not only because most entrenched cultural practices have some positive rationale but also because change as such can be stressful, and side effects are often unanticipated.5 Nevertheless, where human welfare can be enhanced with minimal disruption, it is morally right to try to bring this about.
From all these perspectives, when a person with dementia is admitted to hospital there is disruption from what normally happens; behaviours and responses are different and often unanticipated, routines are broken and the consequence of this is difficulty and distress.
Maintaining biological activity at all despite the absence of conserved thioether rings present in Halα was unanticipated as these motifs are generally considered to be the basis of lantibiotic bioactivity and disruption of a ring has often resulted in abolished activity (1, 34− 34−.
Moreover, according to Ricardo Hausman at Harvard's Kennedy School, "We may see financial disruptions triggered by over-leveraged oil-exporting countries and corporations that could then spread in unanticipated ways".
This was not unanticipated.
