Ultimately, quantitative analysis of immune responses can facilitate discovery in settings where gene modification is impractical, as in primary human cells, or where the direct and indirect effects of genetic alterations mask subtle or unanticipated interactions (Sontag et al., 2004).
Heller said trigger selling brought on by unanticipated events — like Treasury Secretary Henry Paulson's recent alterations to the Troubled Asset Relief Program (See "TARP Changes Colors" )– is creating more panic than hedge fund redemptions, which have already been anticipated by sophisticated market watchers.
Perhaps more important than the reduction of future diversification relative to historical baselines, gradient flattening may impose evolutionary limits upon species' ability to persist in the face of future environmental change, whether due to continuing habitat alteration, invasive species, global warming, or some other novel, unanticipated perturbation.
Further, rapid ecological changes associated with anthropogenic alteration of natural ecosystems can promote contemporary evolution, with unanticipated consequences.
A key unanticipated finding in this study is that SCOP/PHLPP1 KOs exhibit alterations in baseline and post-injury physiology which may be important.
Markedly, however, none of the modification guide snoRNAs showed such strong alteration in any helicase mutant, suggesting that their binding and release involve unanticipated mechanisms.
Genomic structural alterations that vary within species, known as large copy number variants, represent an unanticipated and abundant source of genetic diversity that associates with variation in gene expression and susceptibility to disease.
Undocumented design changes: During implementation, project staff may introduce alterations in project design and intended outcomes that they believe are necessary accommodations to get past unanticipated hurdles or design oversights.
This was not unanticipated.
This led to unanticipated loans.
(ii)Unanticipated bypass.
