Consider an unambiguous mapping of target ranges to phases over the whole transmitted bandwidth requires N-order Costas coded waveform, of duration T, at Nyquist rate.
Already in the stage of requirement engineering, the functions from the function taxonomy are used for the requirement specification, which ensures an unambiguous mapping of requirements to devices and corresponding profiles in the later design phases.
This, in combination with the high repetitive content of the human genome, makes unambiguous mapping difficult, especially for short sequences.
The unambiguous mapping of the CLIP tags allowed us to match the CLIPs to Ensembl gene ids.
Although sequence identity hinders unambiguous mapping of this transcript, the novel first exon splices into exon 4 of the adjacent NAIP1 and/or NAIP2.
We reasoned, that this observation could be attributed to recent gene duplications, which resulted in almost identical gene copies preventing unambiguous mapping.
This small query sequence provided sufficient adjacent, unique sequence to allow for unambiguous mapping of Alu-containing DNA to a single locus in the human genome.
As this phenomenon would prevent the unambiguous mapping of reads to one gene, we only used genes that were encoded by a different genomic stretch of DNA.
Such reads may represent highly conserved sequences that hit multiple genomes making unambiguous mapping impossible, had too few high-quality bases, or they may represent an unknown source of sequence library contamination.
