This shortcoming affects particularly signaling pathways: without solid, consistent and unambiguous representations, hypotheses and analyses based on them are affected by an inability to do any proper computational analysis in the worst case, and a loss of power, in the best case.
The model consistent with the latter hypothesis received unambiguous statistical support in all six P. damicornis colonies analysed.
However, several studies in eudicot species have failed to provide unambiguous support for a hypothesis that development of unisexual flowers would involve alterations in the expression patterns of the B- or C-function genes, which indicates that the genetic mechanisms in sex determination must act downstream of organ identity [ 60- 64].
However, the use of experimental manipulations provides unambiguous support for the hypothesis that radioactive fallout is the likely cause of the abnormalities observed in the field and this effectively counters all of the major criticisms that have been levied at this study.
Once you get up to a certain stage, things become somehow big enough that the hypotheses become unambiguous, and then from that, you can go down and resolve anything below that.
In fact, the inability of macrophages to perform phagocytosis of capped lymphocytes (where antibody-bound surface Ig was polarized to one end of the lymphocyte) was a key finding that provided an elegant and unambiguous proof of the zipper hypothesis for phagocytosis [11].
Some strains of Dehalococcoides contain unambiguous prophages, providing an alternative hypothesis for the mechanism of ssrA-GI transfer, via illegitimate packaging of the excised ssrA-GI into a phage capsule.
While the specific gene(s) and molecular mechanisms producing blue eggs remain unknown, our data provide the first unambiguous evidence for the long-standing hypothesis that egg colouration in brood-parasitic cuckoos is maternally inherited.
These results suggest that (i) analyses of 1D data based on 0D models of randomness are generally biased unless one explicitly identifies 0D variables before the experiment, and (ii) parametric and non-parametric 1D hypothesis testing provide an unambiguous framework for analysis when one׳s hypothesis explicitly or implicitly pertains to whole 1D trajectories.
This biogeographic hypothesis fits the three unambiguous described cases involving Madagascar and Indo-Malaya, or Madagascar and the Seychelles (Hypsipetes, Otus and the Zosterops borbonicus lineage).
Based on our data, we cannot rule out any of these hypotheses, nor provide an unambiguous explanation for the observed pattern.
