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Only tumours with a confirmed unaltered status for all three chromosome arms were considered as having no segmental chromosomal alterations.
The presence of any segmental chromosomal alteration in a tumour (chromosome 1p deletion and/or 11q deletion and/or chromosome 17q gain) was taken into account to define a segmental genomic profile, whereas those tumours with a confirmed unaltered status for all three chromosome arms were considered as having no segmental changes.
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Minimal HE was considered in patients with unaltered neurological status but with alterations in spectral analysis of EEG (i.e. grade ≥ 1 according to the system proposed by Amodio P. et al).
Although the underlying cause of some MCI cases might not be AD [ 5], the progression from MCI to AD happens at a higher rate than that from an unaltered cognitive status [ 6], making MCI a primary endpoint in several randomized controlled trials [ 7– 9] and MCI to AD progression the outcome of several studies predicting future cognitive decline [ 10– 10].
This distribution is unaltered by resistance status or the resistance reversing agent verapamil.
Hepatocyte status remained unaltered and granulomas were not remarkably changed in size or cellularity.
After treatment with somatostatin hepatocyte status remained unaltered, granulomas were not remarkably changed in size or cellularity (results not shown).
The indomethacin administration immediately reduced the mucin secretion in the ulcerated mice compared to that in normal mice (36.4%, P < 0.05) and the status remained unaltered even at peak ulceration.
This included BDNF, which was only expressed in satellite cells and this may be disease specific as it has been found to be unaltered by physical activity status in humans or rodents [ 18, 73].
Thus, the reduced nuclear volume in cells with activated BXB-ER correlated with global condensation of heterochromatin and genome compaction, even though the transcriptional status of nucleoli is unaltered.
The results revealed that the phosphorylation status of eIF2alpha remains unaltered in cells lacking TRAF6, as compared with control RNAi-treated cells (Supplementary Figure 2b).
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