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Although the topology of the recovered tree in the primary phylogenetic analysis (Figure 51) appears unaffected by missing data and homoplastic characters, a closer examination of character state distribution across Allosauroidea reveals a large amount of homoplasy.
In the placebo/PR groups, mean EQ-5D VAS did not return to values similar to baseline until Week 72 in either study.Sensitivity analyses in each study, including a LOCF approach, and comparison of patients with and without baseline FSS scores in the PILLAR study indicated that the EQ-5D VAS results were unaffected by missing data.
Sensitivity analyses in both studies, including a LOCF approach, and comparison of characteristics of patients with and without baseline FSS data in the PILLAR study (Table 3), indicated that the FSS results were unaffected by missing data.> -wrap-foot> †Median; ‡NS5B sequence-based assay.
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The study was affected by missing data.
Mixed models are also unaffected by randomly missing data and therefore do not require imputation methods.
Our conclusions were unaffected by the sensitivity analysis for missing data.
Importantly, the estimates of πN, πS, dN, dS, and α were essentially unaffected by the error model and the missing data cleaning stringency applied.
Percentage of missing data, by locus.
Numbers of births with missing data, by type of data.
The missing data mechanism is modeled by nonparametric prior processes.
Blanks indicate missing data.
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