Spreading of [C]inulin, an extracellular space marker, was unaffected by activation, suggesting that glutamine and lactate may have diffused, in part, through intracellular routes.
Unlike when morphine was used as the agonist, the peak inhibition caused by DAMGO was completely unaffected by activation of PKC with PMA demonstrating an agonist-specific effect of PMA.
At fast voltammetric scan rates the linear diffusion electroactive area was unaffected by iridium activation.
Celecoxib increased p38 MAP kinase (p38), p44/42 MAP kinase (ERK), and p70S6 kinase (p70S6K) phosphorylation while leaving JNK activation unaffected.
Also, when GLT-1 was conditionally knocked out from VTA astrocytes, the IPSC amplitude on DA neurons was unaffected by astrocyte activation paired with electrical stimulation (GLT-1 cKOVTA Astrocyte; Elec = 51.7 ± 9.5 pA, Elec + ChR2 = 52.4 ± 10.2; paired t-test t(7) = 0.2926, P = 0.77, n = 8 cells, 2 mice; Fig. 3h).
In contrast to the isoforms of genes such as CD45 [24] the ratio was apparently unaffected from the activation status of the cells.
Constitutive kinase activity has been observed when full length MEKK1 is cleaved at its caspase recognition site, and mutation of this site inhibits apoptosis normally seen with overexpression in 293T cells while leaving JNK activation unaffected [17].
The loadings of MWNTs in the CNFs were assumed to be unaffected by the activation process.
Histone3 rRNA, which is unaffected by cell activation state, was used to normalize expression of analyzed cytokines transcripts.
Additionally, elements within the bZIP DNA-binding domain are significantly destabilized, whereas the N-terminal domain and bZIP LOV linker region are mainly unaffected by LOV activation.
