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However, the FoxO1 S218DNA-bindingng domain was unable to bind to this sequence (Fig. 3b).
iCLIP with an Aub mutant that is unable to bind piRNAs confirms piRNA-dependent binding of Aub to mRNAs.
P-TEFb is unable to bind to HEXIM1 unless the dsRNA binding domain of HEXIM is occupied [55].
NsrR was unable to bind to DNA fragments lacking an NsrR binding site (data not shown).
The second, P4, alters the binding site on MKKs so that YopJ is unable to bind and modify the kinase.
Instead, the protein broke, unable to bind to any hormone.
First it will be glassy, thin "shuga", "grease" or "pancake" ice, unable to bind the floes together.
Juno belongs to a family of "folate receptor" proteins, but unlike its brethren is unable to bind to folic acid.
mutants that are unable to bind Plk1 fail to restart the cell cycle after ionizing radiation-mediated cell cycle arrest.
Additionally, mutant USP8, which is unable to bind to SFN, reduces the expression of RTKs and p-STAT3.
DSG2 was also shown to be unable to bind HAdV-D26K or HAdV-D48K at any concentration by SPR.
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