We are unable to generate loss-of-function mosaic clones because the Dnhe2 genomic locus is too close to the nearest flippase recognition site (FRT40A).
The problem for social democratic parties across Europe is that – scared in many cases of being viewed as anti-European – they have accepted the iron logic of the Bundesbank's dogma, and are unable to offer an alternative of generating internal European demand.
Expression of the human ALK mutations ALKwt, ALKT1087I, ALKD1091N, ALKA1099T, ALKT1151M, ALKA1234T and ALKR1464STOP were unable to generate formation of foci greater than that of the vector control or ALK wild-type control.
The model is unable to generate a number of classes of transitions.
The Sooners labored in their opener, unable to generate much of a running game or get anything downfield.
10.7554/eLife.00863.005 Figure 3. Chromatin remodeling-defective yChd1 proteins are unable to generate arrays of evenly-spaced nucleosomes during chromatin assembly.
It took nearly 6 months to identify the index case; events transpired so quickly that manual laboratory methods were unable to generate all of the information that was needed.
Neutrophils from CGD patients are unable to generate normal amounts of O2− owing to the loss of components of the NADPH-oxidase complex (reviewed in Segal et al. 2000; Heyworth et al. 2003; Malech and Hickstein 2007).
But through the first half of 2014, it ranked in the bottom third of most categories, unable to generate the pass rush it needed to disrupt the timing of offenses.
Finally, we found that some participants were unable to generate any pros of smoking or cons of quitting.
