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Ultrastructural examination of thyroid follicular cells of this group that received TBT + GTE Groupp III) showed marked improvement of most of the examined follicular cells.
Ultrastructural examination of purified MVA showed that most of the viral particles are enveloped in contrast to the Copenhagen strain (COP).
Ultrastructural examination of the seminiferous tubules revealed thickened boundary tissue, pyknosis of Sertoli cell nuclei, damaged mitochondria and smooth endoplasmic reticulum-derived vacuoles.
Ultrastructural examination of thyroid follicular cells of the control group (Group I) showed a flattened to cuboidal cell with a microvillous border and an oval to rounded euchromatic nucleus.
Groundbreaking advances in volume electron microscopy and specimen preparation are enabling the 3-dimensional visualisation of specimens with unprecedented detail, and driving a gratifying resurgence of interest in the ultrastructural examination of cellular systems.
Furthermore, ultrastructural examination of neurons in treated mice revealed few to no PCBs and no other detectable morphological alterations.
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Ultrastructural examinations of the sensory hair cells revealed that they had obviously not been affected by GM-treatment (no degenerative morphological features observed).
The clinicopathological correlation in this report is limited by the lack of autofluorescence and OCT findings in the eye examined by EM and by the absence of tissue for histological or ultrastructural examination for the clinical cases.
On ultrastructural examination some of the glomerular capillary loops showed subendothelial expansion with granular material and new basement membrane formation, resulting in double contours.
For ultrastructural examination, tissues of the CADASIL foetus (brain, heart, extremity (skin and muscle) and placenta) and the control foetus (brain, lung, extremity (skin and muscle) and placenta) were fixed in 1.5% glutaraldehyde and 1% paraformaldehyde in cacodylate buffer, post-fixed in 1% osmium tetroxide and processed for Spurr embedding.
Ultrastructural examination showed evidence of subendocardial injury, with dilatation of sarcoplasmic reticulum, margination and clumping of nuclear chromatin, and mitochondrial swelling.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com