Sentence examples for ultimately premature from inspiring English sources

5 Chronic untreated HIV, HCV and HBV can manifest as debilitating immune-compromise, hepatic fibrosis and failure, and ultimately premature death.

If youth living with HIV (YLWH) do not receive consistent health care, they are at risk for anti-retroviral (ARV) treatment failure, opportunistic infections, increased risk of sexual HIV transmission, and ultimately premature death [ 7– 9].

Geneticists have long since identified the obesity gene (FTO) 5 and a low-fat gene (APOA5), 6 and that variations in the adiponectin gene (single nucleotide polymorphism [SNP] 276 G allele) can lead to hypoadiponectinemia, which then results in insulin resistance, the metabolic syndrome, increased atherosclerosis, morbidity, and ultimately, premature mortality.

It is tempting but ultimately premature to draw any conclusions about the relative efficacy and safety of the various closed-loop systems, as the populations and clinical protocols are quite different: adults versus children, exercise component versus sedentary only, small versus large meals, and premeal bolus versus no premeal bolus.

The excess production of androgens and estrogens ultimately causes premature closure of the epiphyses and short stature.

They may be set free once people realize they are in over their heads, ultimately facing premature death in the wild by starvation or extremes of climate.

This results in serious developmental setbacks, such as the inability to talk, walk, or breathe independently, and ultimately causes premature death.

Prolonged stress due to protein accumulation in the rER ultimately causes premature chondrocyte cell death [11], [13], [37], [38].

These pathological accumulations at the nuclear envelope cause severe alterations in nuclear morphology and organization, hampering the normal functions of cells and leading ultimately to premature aging phenotypes exhibited by affected patients [ 6].

Such opening of interaction surfaces might increase 'premature' interactions of cargo proteins actually destined for AZ assembly, thus increase overall size of the cargo complexes by oligomerization between AZ proteins and, finally, promote premature capture and ultimately ectopic AZ-like assembly.

They ultimately result in premature tooth loss and therefore diminishing the quality of life.